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HEMOGLOBIN, SICKLE
Descriptors Found:
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DeCS
Descriptor
English
:
Hemoglobin, Sickle
Descriptor
Spanish
:
Hemoglobina Falciforme
Descriptor
Portuguese
:
Hemoglobina Falciforme
Synonyms
English
:
Hemoglobin S
Tree Number:
D12.776.124.400.463.588
D12.776.422.316.762.426.588
Definition
English
:
An abnormal hemoglobin resulting from the substitution of
valine
for
glutamic acid
at position 6 of the beta chain of the
globin
moiety. The heterozygous state results in
sickle cell trait
, the homozygous in sickle cell
anemia.
Indexing Annotation
English
:
/urine
: coord IM with
HEMOGLOBINURIA
(IM);
hemoglobin S disease
=
ANEMIA
, SICKLE CELL; DF: HBS
History Note
English
:
77(75); was HEMOGLOBIN S 1973-74 (Prov)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
22197
Unique Identifier:
D006451
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS